Bithionol (Standard)

• Description:

  Bithionol (Standard) is the analytical standard of Bithionol. This product is intended for research and analytical applications. Bithionol is an antibacterial, anthelmintic, and algaecide agent. Bithionol is also a potent inhibitor of soluble adenylyl cyclase through binding to the allosteric activator site (IC50: 4 μM) [1][2].

• UNSPSC:

  12352005

• Target:

  Bacterial; Parasite; Reference Standards

• Type:

  Reference Standards

• Related Pathways:

  Anti-infection; Others

• Field of Research:

  Cancer; Infection

• Assay Protocol:

  https://www.medchemexpress.com/bithionol-standard.html

• Smiles:

  OC1=C(Cl)C=C(Cl)C=C1SC2=CC(Cl)=CC(Cl)=C2O

• Molecular Formula:

  C12H6Cl4O2S

• Molecular Weight:

  356.05

• References & Citations:

  [1]Florent RL, et al. In vitro toxicity of bithionol and bithionol sulphoxide to Neoparamoeba spp., the causative agent of amoebic gill disease (AGD) . Dis Aquat Organ. 2010 Sep 17;91 (3) :257-62.|[2]Silke Kleinboelting, et al. Bithionol Potently Inhibits Human Soluble Adenylyl Cyclase through Binding to the Allosteric Activator Site. J Biol Chem. 2016 Apr 29;291 (18) :9776-84. |[3]J Maki, et al. Anthelmintic effects of bithionol, paromomycin sulphate, flubendazole and mebendazole on mature and immature Hymenolepis nana in mice. J Helminthol. 1985 Sep;59 (3) :211-6.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference Standards

• CAS Number:

  [97-18-7]