SPDB

SPDB

• CAS Number: 115088-06-7
• UNSPSC Description: SPDB is a glutathione cleavable ADC linker used for the antibody-drug conjugate (ADCs)[1].
• Target Antigen: ADC Linker
• Type: ADC Related
• Related Pathways: Antibody-drug Conjugate/ADC Related
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/SPDB.html
• Purity: 99.16
• Solubility: DMSO : 100 mg/mL (ultrasonic)|Ethanol : 100 mg/mL (ultrasonic)
• Smiles: O=C(CC1)N(OC(CCCSSC2=NC=CC=C2)=O)C1=O
• Molecular Weight: 326.399
• References & Citations: [1]Widdison WC et al. Development of Anilino-Maytansinoid ADCs that Efficiently Release Cytotoxic Metabolitesin Cancer Cells andInduce High Levels of Bystander Killing.
 Bioconjug Chem, 2015 Nov 18, 26(11):2261-78.
• Shipping Conditions: Blue Ice
• Storage Conditions: -20°C (Powder, sealed storage, away from moisture)
• Clinical Information: No Development Reported