Guvacoline (hydrobromide)

• UNSPSC Description:

  Guvacoline hydrobromide, a pyridine alkaloid found in Areca triandra, can act as a weak full agonist of atrial and ileal mAChR[1][2].

• Target Antigen:

  mAChR

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein;Neuronal Signaling

• Field of Research:

  Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/guvacoline-hydrobromide.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(C1=CCCNC1)OC.Br

• Molecular Weight:

  222.08

• References & Citations:

  [1]Jiao Wu, et al. Tissue-specific and maturity-dependent distribution of pyridine alkaloids in Areca triandra. J Plant Res. 2019 Jul;132(4):531-540.|[2]M Wolf-Pflugmann, et al. Synthesis and muscarinic activity of a series of tertiary and quaternary N-substituted guvacine esters structurally related to arecoline and arecaidine propargyl ester. Arzneimittelforschung. 1989 May;39(5):539-44.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  17210-51-4