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Guvacoline (hydrochloride)

CAT: 0804-HY-N5016-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N5016-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Guvacoline hydrochloride, a pyridine alkaloid found in Areca triandra, can act as a weak full agonist of atrial and ileal muscarinic receptors[1][2].
CAS Number
6197-39-3
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
MAChR
Type
Natural Products
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/guvacoline-hydrochloride.html
Purity
98.0
Solubility
DMSO : 100 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)
Smiles
O=C(C1=CCCNC1)OC.[H]Cl
Molecular Formula
C7H12ClNO2
Molecular Weight
177.63
Precautions
H302, H315, H319, H335
References & Citations
[1]Jiao Wu, et al. Tissue-specific and maturity-dependent distribution of pyridine alkaloids in Areca triandra. J Plant Res. 2019 Jul;132 (4) :531-540.|[2]M Wolf-Pflugmann, et al. Synthesis and muscarinic activity of a series of tertiary and quaternary N-substituted guvacine esters structurally related to arecoline and arecaidine propargyl ester. Arzneimittelforschung. 1989 May;39 (5) :539-44.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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