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Levamlodipine (hydrobromide)

CAT: 0804-HY-14744CSize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-14744CSize:1 Each
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Description
Levamlodipine hydrobromide is the besylate hydrobromide salt form of Levamlodipine. Levamlodipine hydrobromide is an orally active calcium channel blocker with antioxidant and vasodilatory properties. Levamlodipine hydrobromide can reduce serum malondialdehyde (MDA) levels, increase superoxide dismutase (SOD) activity, and improve oxidative stress. Levamlodipine hydrobromide can be used for research on vascular dementia, hypertension, and cerebrovascular diseases[1][2][3][4].
CAS Number
865430-78-0
Product Name Alternative
(S) -Amlodipine (hydrobromide) ; Levoamlodipine (hydrobromide)
UNSPSC
12352005
Target
Calcium Channel; SOD
Type
Reference compound
Related Pathways
Immunology/Inflammation; Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Others; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/levamlodipine-hydrobromide.html
Smiles
O=C(C1=C(COCCN)NC(C)=C(C(OC)=O)[C@@H]1C2=CC=CC=C2Cl)OCC.Br
Molecular Formula
C20H26BrClN2O5
Molecular Weight
489.79
References & Citations
[1]Yao KX, et al. Effect of low-dose Levamlodipine Besylate in the treatment of vascular dementia. Sci Rep. 2019 Dec 3;9 (1) :18248.|[2]Rong H, et al. [Effect of probucol on serum malondialdehyde and superoxide dismutase in patients with primary hypertension]. Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2012 May;37 (5) :458-62.|[3] Yang YL, et al. Synergic effects of levamlodipine and bisoprolol on blood pressure reduction and organ protection in spontaneously hypertensive rats. CNS Neurosci Ther. 2012 Jun;18 (6) :471-4.|[4]Lee YJ, et al. Amlodipine besylate and amlodipine camsylate prevent cortical neuronal cell death induced by oxidative stress. J Neurochem. 2011 Dec;119 (6) :1262-70.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 4

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