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Anticancer agent 231

CAT: 0804-HY-162575Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-162575Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Anticancer agent 231 (Compound P5) is a tyrosine protein kinase inhibitor with a IC50 value of 3.95 μM. Anticancer agent 231 inhibits the cell viability, cell proliferation, cell migration and cancer dryness of triple negative breast cancer (TNBC) cells by targeting EGFR-ERK 1/2 signaling pathway, and is expected to play an important role in the field of TNBC disease therapy[1].
CAS Number
[128519-30-2]
UNSPSC
12352005
Target
ERK
Type
Reference compound
Related Pathways
MAPK/ERK Pathway; Stem Cell/Wnt
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/anticancer-agent-231.html
Smiles
ClC1=CC=C(C2=NN(C3=CC=CC=C3)C(C4=CC=C(N(C)C)C=C4)C2)C=C1
Molecular Formula
C23H22ClN3
Molecular Weight
375.89
References & Citations
[1]Satriyo PB, et al. N-phenyl pyrazoline derivative inhibits cell aggressiveness and enhances paclitaxel sensitivity of triple negative breast cancer cells. Sci Rep. 2024 Jun 8;14 (1) :13200.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
ERK1; ERK2

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