5-Methylurapidil

• UNSPSC Description:

  5-Methylurapidil isα1A‐adrenoceptor antagonist. 5-Methylurapidil can be used for the research of cardiovascular diseases such as hypertension and heart failure[1].

• Target Antigen:

  Adrenergic Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein;Neuronal Signaling

• Field of Research:

  Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/5-methylurapidil.html

• Purity:

  98.0

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C1N(C(C(C)=C(N1C)NCCCN2CCN(CC2)C3=CC=CC=C3OC)=O)C

• Molecular Weight:

  401.50

• References & Citations:

  [1]Arce C, et al. Activation of α1A -adrenoceptors desensitizes the rat aorta response to phenylephrine through a neuronal NOS pathway, a mechanism lost with ageing. Br J Pharmacol. 2017 Jul;174(13):2015-2030.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  34661-85-3