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5-Methylurapidil

CAT: 0804-HY-120296-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-120296-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
5-Methylurapidil isα1A‐adrenoceptor antagonist. 5-Methylurapidil can be used for the research of cardiovascular diseases such as hypertension and heart failure[1].
CAS Number
34661-85-3
UNSPSC
12352005
Target
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/5-methylurapidil.html
Purity
98.0
Solubility
10 mM in DMSO
Smiles
O=C1N(C(C(C)=C(N1C)NCCCN2CCN(CC2)C3=CC=CC=C3OC)=O)C
Molecular Formula
C21H31N5O3
Molecular Weight
401.50
References & Citations
[1]Arce C, et al. Activation of α1A -adrenoceptors desensitizes the rat aorta response to phenylephrine through a neuronal NOS pathway, a mechanism lost with ageing. Br J Pharmacol. 2017 Jul;174 (13) :2015-2030.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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