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YMEL1 rabbit pAb

CAT: 0855-ES12257-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES12257-01Size:50 µL
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Background
The protein encoded by this gene is the human ortholog of yeast mitochondrial AAA metalloprotease, Yme1p. It is localized in the mitochondria and can functionally complement a yme1 disruptant yeast strain. It is proposed that this gene plays a role in mitochondrial protein metabolism and could be involved in mitochondrial pathologies. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
Description
The protein encoded by this gene is the human ortholog of yeast mitochondrial AAA metalloprotease, Yme1p. It is localized in the mitochondria and can functionally complement a yme1 disruptant yeast strain. It is proposed that this gene plays a role in mitochondrial protein metabolism and could be involved in mitochondrial pathologies. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011],
Product Name Alternative
ATP-dependent zinc metalloprotease YME1L1 (EC 3.4.24.-) (ATP-dependent metalloprotease FtsH1) (Meg-4) (Presenilin-associated metalloprotease) (PAMP) (YME1-like protein 1)
UniProt
Q96TA2
Swiss Prot
Q96TA2
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from human YMEL1 AA range: 136-186
Target
YMEL1
Clonality
Polyclonal
Source
Rabbit
Applications
WB
Concentration
1 mg/ml
Dilution
WB 1:500-2000
Buffer
-20°C/1 year
Molecular Weight
85kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
85kD
Fragment
IgG
Subcellular Location
Mitochondrion inner membrane . Mitochondrion .
Other Product Names
ATP-dependent zinc metalloprotease YME1L1 (EC 3.4.24.-) (ATP-dependent metalloprotease FtsH1) (Meg-4) (Presenilin-associated metalloprotease) (PAMP) (YME1-like protein 1)
Gene ID (Human)
10730

UniProtKB · Q96TA2

ATP-dependent zinc metalloprotease YME1L1

YMEL1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q96TA2
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
YME1L1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
3.4.24.-, 3.6.-.-
Processing
—
Secondary accessions
B4DNM1, D3DRV8, D3DRV9, Q5T8D9, Q9H1Q0, Q9UMR9
Protein keywords

Coding sequence diversity

Alternative splicing

Ligand

ATP-bindingMetal-bindingNucleotide-bindingZinc

Disease

Disease variant

Molecular function

HydrolaseMetalloproteaseProtease

Cellular component

MembraneMitochondrionMitochondrion inner membrane

Technical term

Proteomics identificationReference proteome

Domain

TransmembraneTransmembrane helix

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