Nav1.8-IN-4

• CAS Number:

  1620846-16-3

• UNSPSC Description:

  Nav1.8-IN-4 (compound 9a) is a Nav1.8 channel inhibitor (IC50=0.014 μM). Nav1.8-IN-4 can be used for research on pain-related diseases[1].

• Target Antigen:

  Sodium Channel

• Type:

  Reference compound

• Related Pathways:

  Membrane Transporter/Ion Channel

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/nav1-8-in-4.html

• Solubility:

  DMSO : 116.67 mg/mL (ultrasonic)

• Smiles:

  O=C1C=C(NC(C2=CC=C(C(F)(F)F)C=C2OC3=CC=C(C=C3C)F)=O)C=CN1

• Molecular Weight:

  406.33

• References & Citations:

  [1]Corey Anderson, et al. Prodrugs of pyridone amides useful as modulators of sodium channels. Patent WO2015089361A1.

• Shipping Conditions:

  Room Temperature

• Clinical Information:

  No Development Reported