10-Boc-SN-38

CAT: 0804-HY-164271Size: 1 EachDry Ice: NoHazardous: No

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Description

10-Boc-SN-38 is a tert-butyloxycarbonyl (Boc) -protected form of SN-38. SN-38 is the active metabolite of Irinotecan (HY-16562).

CAS Number

362497-15-2

UNSPSC

12352203

Target

Topoisomerase

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/10-boc-sn-38.html

Smiles

CCC1=C2C(C(N3C2)=CC([C@](O)(C(OC4)=O)CC)=C4C3=O)=NC5=CC=C(OC(OC(C)(C)C)=O)C=C51

Molecular Formula

C27H28N2O7

Molecular Weight

492.52

References & Citations

[1]Charlotte C Williams, et al. RAFT-derived polymer-drug conjugates: poly (hydroxypropyl methacrylamide) (HPMA) -7-ethyl-10-hydroxycamptothecin (SN-38) conjugates. ChemMedChem. 2012 Feb 6;7 (2) :281-91.

Shipping Conditions

Room temperature

Scientific Category

ADC Related

Clinical Information

No Development Reported

Related Products

Catalog	Name
HY-13704-01	SN-38
HY-13704R-01	SN-38 (Standard)
HY-126373-01	SN-38 glucuronide
HY-128946-01	CL2A-SN-38
HY-126350-01	CL2-SN-38
HY-157797	SN-38-CM2
HY-13704S-01	SN-38-d3
HY-W653919	SN-38 glucuronide-d3
HY-126373S1-01	SN-38 glucuronide-13C6
HY-145767A-01	SN-38-CO-DMEDA (TFA)

Alternative Products

Catalog	Name
BIPG2099-01	Boc-O-SN-38
MBS6083380-01	10-O-Methoxymethyl SN-38
TRC-A187735-2MG	10-O-Acetyl SN-38
BUP14103-01	SN-38
sc-203697	SN 38

10-Boc-SN-38

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