Claudin 1 Recombinant Rabbit Monoclonal Antibody [JE30-33]

Claudin 1 Recombinant Rabbit Monoclonal Antibody [JE30-33]

• Description: Claudin-1 is a protein that in humans is encoded by the CLDN1 gene. It belongs to the group of claudins. Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are composed of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome.
• Product Name Alternative: Claudin-1 antibody Claudin1 antibody CLD 1 antibody CLD1 antibody CLD1_HUMAN antibody CLDN 1 antibody Cldn1 antibody ILVASC antibody SEMP 1 antibody SEMP1 antibody Senescence associated epithelial membrane protein 1 antibody Senescence associated epithelial membrane protein antibody Senescence-associated epithelial membrane protein antibody
• Abbreviation: CLDN1, CLD1, SEMP1
• CAS Number: 9000-83-3
• Swiss Prot: O95832 Human, O88551 Mouse, P56745 Rat
• Cellular Locus: Cell junction, tight junction, Cell membrane, Basolateral cell membrane.
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Synthetic peptide within Human Claudin 1 aa 164-211 / 211.
• Isotype: IgG
• Clone: JE30-33
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB, IHC-P
• Positive Control: A431 cell lysate, HUVEC cell lysate, Caco-2 cell lysate, mouse skin tissue lysate, mouse liver tissue lysate, rat skin tissue lysate, rat liver tissue lysate, human esophageal cancer tissue, human skin tissue, mouse skin tissue, rat skin tissue.
• Concentration: 1 mg/mL
• Dilution: WB: 1:2,000 ;IHC-P: 1:500
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 23 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: Yes