Products for Research Use Only
RegisterLogin

TAX2 peptide

CAT: 0804-HY-P10388-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-P10388-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
TAX2 peptide is a dodecapeptide based on molecular docking and simulation design, derived from the cell surface receptor CD47 sequence. TAX2 peptide acts as a selective antagonist of TSP-1 (thromboxin-1) interacting with CD47. TAX2 peptide can promote the binding of TSP-1 to CD36, which leads to the destruction of VEGFR2 (vascular endothelial growth factor receptor 2) activation, thereby blocking downstream NO (nitric oxide) signaling, demonstrating anti-angiogenic properties. TAX2 peptide can be used to study angiogenesis and tumor cell interactions in the tumor microenvironment[1].
UNSPSC
12352209
Target
CD47; TGF-β Receptor
Type
Peptides
Related Pathways
Immunology/Inflammation; TGF-beta/Smad
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tax2-peptide.html
Purity
98.70
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C([C@@H](N)CSSC[C@H](NC1=O)C(O)=O)N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H]1C)=O)CC(O)=O)=O)=O)CCCCN)=O)CC(C)C)=O)CC(C)C)=O)CCC(N)=O)=O)CO)=O)C(C)C)=O)CCC(O)=O
Molecular Formula
C51H86N14O19S2
Molecular Weight
1263.44
References & Citations
[1]Jeanne A, et al. Identification of TAX2 peptide as a new unpredicted anti-cancer agent[J]. Oncotarget, 2015, 6 (20) : 17981.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported

Related Products

CatalogName
HY-P11394Fibronectin binding protein peptide, D3 peptide
HY-P11350A666 peptide
HY-P11328GFOGER peptide
HY-P11315MG1 peptide
HY-P11285LAGIPRA peptide
HY-P11119CKS peptide
HY-P11062M30 peptide
HY-P11033Pep2 Peptide
HY-P10967EGFR Peptide
HY-P10942CGN peptide

Alternative Products

CatalogName
TP3587-01TAX2 peptide
CRB1001338-01GRGDS peptide - (Peptide)
CRB1001125-01GALA Peptide - (Peptide)
CRB1000885-01DAG peptide - (Peptide)
CRB1000666-01SMRT peptide - (Peptide)
CRB1001290-01LDVP peptide - (Peptide)
CRB1001012-01RGD peptide - (Peptide)
GTR18890997Peptide B peptide
DF8746-BPASAP1 Peptide Peptide
GTR18891000Peptide YY peptide

Popular Products