CGN peptide

• Description :

  CGN peptide is a 13 amino acid peptide composed of D-amino acids, referred to as CGN peptide. CGN peptide is the retro-inverso isomer of the l-peptide TGN (TGNYKALHPHNG) and can deliver siRNA to the blood-brain barrier (BBB) . CGN peptide can be used in Alzheimer's disease (AD) research[1].

• UNSPSC :

  12352209

• Target :

  Small Interfering RNA (siRNA)

• Related Pathways :

  Epigenetics

• Applications :

  Neuroscience-Neurodegeneration

• Field of Research :

  Neurological Disease

• Smiles :

  O=C(NCC(N[C@H](CC(N)=O)C(N[C@H](CC1=CNC=N1)C(N2[C@H](CCC2)C(N[C@H](CC3=CNC=N3)C(N[C@H](CC(C)C)C(N[C@H](C)C(N[C@H](CCCCN)C(N[C@H](CC4=CC=C(C=C4)O)C(N[C@H](CC(N)=O)C(NCC(N[C@H]([C@@H](O)C)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@@H](CS)N

• Molecular Formula :

  C60H90N20O18S

• Molecular Weight :

  1411.54

• References & Citations :

  [1]Zheng X, et al. A hybrid siRNA delivery complex for enhanced brain penetration and precise amyloid plaque targeting in Alzheimer's disease mice. Acta Biomater. 2017 Feb;49:388-401.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Peptides

• Clinical Information :

  No Development Reported

• CAS Number :

  [2421211-40-5]