TAX2 peptide
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
TAX2 peptide
Target :
TGF-beta/SmadRelated Pathways :
Stem CellsBioactivity :
TAX2 peptide is a novel dodecapeptide designed through molecular docking and simulation, originating from the sequence of the cell surface receptor CD47. As a selective antagonist of the TSP-1 (thrombospondin-1) and CD47 interaction, TAX2 peptide enhances the binding of TSP-1 to CD36. This disrupts the activation of VEGFR2 (vascular endothelial growth factor receptor 2), blocking downstream NO (nitric oxide) signaling and exhibiting anti-angiogenic properties. TAX2 peptide is useful for studying angiogenesis and tumor cell interactions within the tumor microenvironment.Molecular Formula :
C51H86N14O19S2Shipping Conditions :
Cool packStorage Temperature :
-20°C
