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TAX2 peptide

CAT: 0931-TP3587-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-TP3587-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
TGF-beta/Smad
Related Pathways
Stem Cells
Bioactivity
TAX2 peptide is a novel dodecapeptide designed through molecular docking and simulation, originating from the sequence of the cell surface receptor CD47. As a selective antagonist of the TSP-1 (thrombospondin-1) and CD47 interaction, TAX2 peptide enhances the binding of TSP-1 to CD36. This disrupts the activation of VEGFR2 (vascular endothelial growth factor receptor 2), blocking downstream NO (nitric oxide) signaling and exhibiting anti-angiogenic properties. TAX2 peptide is useful for studying angiogenesis and tumor cell interactions within the tumor microenvironment.
Molecular Formula
C51H86N14O19S2
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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