Wnt/β-catenin-IN-2

• UNSPSC Description:

  Wnt/β-catenin-IN-2 (Compound 3235-0367) is a Wnt/β-catenin signaling pathway inhibitor, with IC50 and KD values of 7.1 and 2.5 μM, respectively. Wnt/β-catenin-IN-2 can be used for the research of cancer[1].

• Target Antigen:

  Wnt; β-catenin

• Type:

  Reference compound

• Related Pathways:

  Stem Cell/Wnt

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/wnt-β-catenin-in-2.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(C1=CC=C(C=C1)OC)NC2=C(C(NC(C(C)C)C(NNC(COC3=CC=CC=C3)=O)=O)=O)C=CC=C2

• Molecular Weight:

  518.56

• References & Citations:

  [1]Lee HJ, et al. Structure-based Discovery of Novel Small Molecule Wnt Signaling Inhibitors by Targeting the Cysteine-rich Domain of Frizzled. J Biol Chem. 2015 Dec 18;290(51):30596-606.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  1397006-01-7