Wnt/β-catenin-IN-3
CAT:
804-HY-158210
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Wnt/β-catenin-IN-3
- CAS Number: 1809413-98-6
- UNSPSC Description: Wnt/β-catenin-IN-3 (compound 17) is a Wnt/β-catenin inhibitor with low micromolarGI50s against various cancer cells. Wnt/β-catenin-IN-3triggers G2/M cell cycle arrest though activation of p53-p21 pathway as well as intrinsic and extrinsic apoptotic death of colon cancer cells[1].
- Target Antigen: MDM-2/p53; Wnt; β-catenin
- Type: Reference compound
- Related Pathways: Apoptosis;Stem Cell/Wnt
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/wnt-β-catenin-in-3.html
- Solubility: 10 mM in DMSO
- Smiles: COC1=CC=C(C=C1)C(NC2=CC(C3=CC(C4=C(C(OC)=C(C=C4O3)OC)OC)=O)=CC=C2)=O
- Molecular Weight: 461.46
- References & Citations: [1]Hassan AHE, et al. Discovery of a stilbenoid-flavanone hybrid as an antitumor Wnt/β-catenin signaling pathway inhibitor. Bioorg Chem. 2024 Apr;145:107178.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported