Dexamethasone (Water Soluble)

• UNSPSC Description:

  Dexamethasone (Hexadecadrol) Water Soluble is a water-soluble form of Dexamethasone (HY-14648). Dexamethasone is a glucocorticoid receptor agonist, apoptosis inducer, and a common disease inducer in experimental animals. It can be used to construct models of muscle atrophy, hypertension, and depression. Dexamethasone can inhibit the production of inflammatory miRNA-155 exosomes in macrophages and significantly reduce the expression of inflammatory factors in neutrophils and monocytes. Dexamethasone also has the potential to be used in COVID-19 research[1].

• Target Antigen:

  Antibiotic; Autophagy; Bacterial; Complement System; Glucocorticoid Receptor; Mitophagy; SARS-CoV

• Type:

  Reference compound

• Related Pathways:

  Anti-infection;Autophagy;Immunology/Inflammation;Vitamin D Related/Nuclear Receptor

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer; Infection; Endocrinology; Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/dexamethasone-water-soluble.html

• Solubility:

  H2O : ≥ 100 mg/mL

• Smiles:

  [Dexamethasone (Water Soluble)]

• References & Citations:

  [1]Piras A M, et al. A water-soluble, mucoadhesive quaternary ammonium chitosan-methyl-β-cyclodextrin conjugate forming inclusion complexes with dexamethasone[J]. Journal of Materials Science: Materials in Medicine, 2018, 29: 1-13.

• Shipping Conditions:

  Blue Ice

• Clinical Information:

  Phase 4

• CAS Number:

  50-02-2