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Cholesterol (Water Soluble)

CAT: 0804-HY-N0322A-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N0322A-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Cholesterol Water Soluble is a major sterol in mammals, constituting 20-25% of the structural composition of the plasma membrane. The plasma membrane is highly permeable to water but relatively impermeable to ions and protons. Cholesterol Water Soluble plays an important role in determining the fluidity and permeability characteristics of membranes and the function of transporters and signaling proteins. Cholesterol Water Soluble is also an endogenous estrogen-related receptor alpha (ERRα) agonist. Cholesterol Water Soluble can be used to study the effects of cholesterol on potassium currents in inner hair cells[1][2]. (Note: This product is a mixture of Cholesterol and Methyl-β-cyclodextrin. The product specifications below only indicate the effective content of Cholesterol.)
UNSPSC
12352211
Target
Liposome
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/cholesterol-water-soluble.html
Purity
98.0
Solubility
DMSO : ≥ 33.33 mg/mL|H2O : 50 mg/mL (ultrasonic)
Smiles
[Cholesterol(WaterSoluble)]
References & Citations
[1]Kimitsuki T. Cholesterol influences potassium currents in inner hair cells isolated from guinea pig cochlea. Auris Nasus Larynx. 2017;44 (1) :46-51. |[2]Nguyen TV, et al. Contribution of membrane cholesterol to outer hair cell lateral wall stiffness. Otolaryngol Head Neck Surg. 1998;119 (1) :14-20.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Natural Products
Clinical Information
Phase 4
Citation 01
Adv Sci (Weinh) . 2023 Sep;10 (27) :e2206878.|Cancer Commun (Lond) . 2025 Aug;45 (8) :1010-1037.|Cell Biosci. 2025 Jul 4;15 (1) :95.|Commun Biol. 2024 Nov 9;7 (1) :1476.|Exp Mol Med. 2025 May;57 (5) :1089-1105.|Immunity. 2024 May 14;57 (5) :1087-1104.e7.|Nat Aging. 2025 Aug 26.|Nat Biomed Eng. 2025 Feb;9 (2) :215-233.|Redox Biol. 2025 Jul:84:103693.|Sci Rep. 2025 May 26;15 (1) :18364.|ACS Appl Mater Interfaces. 2024 Sep 4;16 (35) :46044-46052.|ACS Appl Mater Interfaces. 2025 Oct 8;17 (40) :55861-55875.|Adv Sci (Weinh) . 2024 Aug 9:e2402329.|Adv Sci (Weinh) . 2024 Jul 1:e2403640.|Adv Sci (Weinh) . 2025 Jun 20:e04195.|Antiviral Res. 2023 Jan:209:105497.|Biochem Biophys Res Commun. 2020 Feb 19;522 (4) :862-868.|Biochem Pharmacol. 2025 Aug 8;242 (Pt 3) :117223.|Biomacromolecules. 2025 Jun 9;26 (6) :3563-3575.|bioRxiv. 2025 January 22.|Cell Biomater. 2025 Aug 19.|Cell Death Discov. 2024 May 29;10 (1) :263.|Cell Death Discov. 2025 Feb 8;11 (1) :55.|Cell Metab. 2024 Nov 5;36 (11) :2402-2418.e10.|Cell Mol Life Sci. 2024 Jul 6;81 (1) :289.|Cell Signal. 2024 Sep 16:111419.|EMBO Mol Med. 2024 Aug;16 (8) :1755-1790.|Free Radic Biol Med. 2024 Aug 27:S0891-5849 (24) 00623-3.|Int J Nanomedicine. 2025 Oct 22:20:12783-12804.|Int J Pharm. 2024 Aug 18:124608.|iScience. 2024 Apr 3.|J Control Release. 2025 May 30:113907.|J Ethnopharmacol. 2025 Apr 24:119877.|J Nanobiotechnology. 2022 Oct 20;20 (1) :454.|J Pharm Sci. 2024 May 25:S0022-3549 (24) 00199-0.|Life Sci Alliance. 2022 Jan 4;5 (3) :e202101256.|Life Sci. 2023 Aug 15:327:121698.|Life Sci. 2025 Jun 1:370:123571.|Mol Cancer. 2025 Jul 19;24 (1) :199.|Mol Cancer. 2025 May 26;24 (1) :151.|Nanomedicine. 2024 Jun:58:102745.|Nat Chem Biol. 2022 Nov;18 (11) :1196-1203.|Nat Commun. 2024 Jan 2;15 (1) :162.|Nat Nanotechnol. 2021 Oct;16 (10) :1150-1160.|Nat Struct Mol Biol. 2025 May;32 (5) :896-904.|Nature. 2025 Jul;643 (8070) :192-200.|NPJ Vaccines. 2025 Aug 14;10 (1) :193.|Part Part Syst Charact. 2024 Jun 12.|Part Sci Technol. 2025 Jul 03.|Patent. US20200376102A1.|Patent. US20200376146A1.|Patent. US20250248939A1.|Pathol Res Pract. 2025 Sep:273:156138.|Phytomedicine. 2024 Mar:125:155299.|Phytomedicine. 2025 May 24:143:156904.|Plant J. 2025 Nov;124 (3) :e70559.|Polym Test. 2023 Dec 1, 108292.|Redox Biol. 2023 Jun:62:102678.|Res Sq. 2025 Jul 29.|Sci China Life Sci. 2022 Feb;65 (2) :341-361.|Signal Transduct Target Ther. 2025 Mar 24;10 (1) :101.|Small Methods. 2025 Apr 21:e2401712.|SSRN. 2024 Feb 5.|SSRN. 2025 Aug 29.|SSRN. 2025 Oct 29.|Theranostics. 2021 Jan 1;11 (2) :841-860.|Traditional Medicine Research. 2025;10 (4) :20.|Vet Microbiol. 2024 Jan:288:109948.|Viruses. 2022 Mar 3;14 (3) :514.

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