E-5531

• Description:

  E-5531 is an endotoxin antagonist. E-5531 quickly becomes inactive after binding with HDL. E-5531 can block the Toll like receptor 4 (TLR4) signaling pathway. E-5531 can be used for the study of endotoxemia and septic shock[1].

• UNSPSC:

  12352005

• Target:

  Toll-like Receptor (TLR)

• Related Pathways:

  Immunology/Inflammation

• Field of Research:

  Inflammation/Immunology

• Smiles:

  CCCCCC/C=C\CCCC(O[C@H](CCCCCCC)CCO[C@@H]1[C@H]([C@@H](O[C@@H]([C@H]1OP(O)(O)=O)COC)OC[C@@H]2[C@H]([C@@H]([C@H]([C@H](O2)OP(O)(O)=O)NC(CC(CCCCCCCCCCC)=O)=O)OCC[C@H](O)CCCCCCC)O)NC(CC(CCCCCCCCCCC)=O)=O)=O

• Molecular Formula:

  C73H136N2O22P2

• Molecular Weight:

  1455.81

• References & Citations:

  [1]Ondiveeran H K, et al. E-5564 Eisai[J]. IDrugs, 2004, 7 (6) : 582-590.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  Phase 2

• CAS Number:

  [162679-36-9]