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Vinclozolin M2

CAT: 0804-HY-130431-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-130431-01Size:5 mg
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Description
Vinclozolin M2 is an active metabolite of vinclozolin. It is formed from vinclozolin by successive esterase activity and decarboxylation of vinclozolin in C. elegans and by decarboxylation in human liver microsomes. Vinclozolin M2 is an antagonist of the mineralocorticoid receptor (IC50=1,400 nM) and androgen receptor (IC50=0.17 nM) in reporter assays using MCF-7 cells.
CAS Number
83792-61-4
UNSPSC
12352005
Target
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/vinclozolin-m2.html
Smiles
C=CC(C)(O)C(NC1=CC(Cl)=CC(Cl)=C1)=O
Molecular Formula
C11H11Cl2NO2
Molecular Weight
260.12
References & Citations
[1]Pothuluri, et al. Biotransformation of vinclozolin by the fungus Cunninghemella elegans. J. Agric. Food Chem. 48 (12), 6138-6148 (2000) .
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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