Gomisin M2

• Description :

  Gomisin M2 ((+) -Gomisin M2) is a lignan isolated from the fruits of Schisandra rubriflora with anti-HIV activity (EC50 of 2.4 μM) . Gomisin M2 exhibits anti-cancer and anti-allergic activities and has the potential for Alzheimer’s disease research[1][2].

• Product Name Alternative :

  (+) -Gomisin M2

• UNSPSC :

  12352005

• Target :

  HIV

• Type :

  Natural Products

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-anti-virus

• Field of Research :

  Cancer; Infection; Inflammation/Immunology; Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/gomisin-m2.html

• Purity :

  99.75

• Solubility :

  10 mM in DMSO

• Smiles :

  OC1=C(OCO2)C2=CC3=C1C4=C(OC)C(OC)=C(OC)C=C4C[C@H](C)[C@H](C)C3

• Molecular Formula :

  C22H26O6

• Molecular Weight :

  386.44

• References & Citations :

  [1]Min Chen, et al. Rubrisandrins A and B, Lignans and Related anti-HIV Compounds From Schisandra Rubriflora. J Nat Prod. 2006 Dec;69 (12) :1697-701.|[2]Hima Dhakal, et al. Gomisin M2 Inhibits Mast Cell-Mediated Allergic Inflammation via Attenuation of FcεRI-Mediated Lyn and Fyn Activation and Intracellular Calcium Levels. Front Pharmacol. 2019 Aug 2;10:869.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, protect from light)

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported

• Isoform :

  HIV

• CAS Number :

  [82425-45-4]