M2 Peptide

• Description :

  M2 Peptide is a peptide targeting M2-like tumor-associated macrophages (TAMs) . M2 Peptide is used to carry drugs or small interfering RNA (siRNA) to promote the repolarization of M2-like macrophages to M1-like macrophages, thereby altering the immunosuppressive state in the tumor microenvironment and enhancing the anti-tumor immune response. M2 Peptide can be used to study the effect of macrophage polarization and how this polarization change affects tumor growth and metastasis[1].

• CAS Number :

  [3098205-40-1]

• UNSPSC :

  12352209

• Target :

  Others

• Type :

  Peptides

• Related Pathways :

  Others

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/m2-peptide.html

• Purity :

  98.26

• Smiles :

  O=C(N[C@@H](CC1=CNC2=CC=CC=C12)C(N[C@@H](CC3=CNC4=CC=CC=C34)C(N[C@@H](CCCCN)C(N[C@@H](C(C)C)C(NCC(N[C@@H](CC5=CNC6=CC=CC=C56)C(N7[C@@H](CCC7)C(N[C@@H](CC(O)=O)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC8=CC=C(C=C8)O)C(N[C@@H](CS)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CC9=CC=C(C=C9)O)N

• Molecular Formula :

  C86H106N18O21S

• Molecular Weight :

  1759.93

• References & Citations :

  [1]Xiao H, et al. M2-like tumor-associated macrophage-targeted codelivery of STAT6 inhibitor and IKKβ siRNA induces M2-to-M1 repolarization for cancer immunotherapy with low immune side effects[J]. ACS central science, 2020, 6 (7) : 1208-1222.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

• Scientific Category :

  Peptides

• Clinical Information :

  No Development Reported