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CTP-amiodarone

CAT: 0804-HY-P10773Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-P10773Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CTP-amiodarone is a cell-penetrating conjugate of cardiomyocyte targeting peptide and Amiodarone. CTP-amiodarone exhibits antiarrhythmic efficacy through block of Na+, K+, Ca2+ channels and β-adrenergic receptors[1].
UNSPSC
12352209
Target
Adrenergic Receptor; Calcium Channel; Peptide-Drug Conjugates (PDCs) ; Potassium Channel; Sodium Channel
Type
Peptides
Related Pathways
Antibody-drug Conjugate/ADC Related; GPCR/G Protein; Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/ctp-amiodarone.html
Smiles
CCCC1=C(C2=C(O1)C=CC=C2)C(C3=CC(I)=C(C(I)=C3)OCC[N+](CC)(CCCCSSCCC(N[C@H](C(N4CCC[C@H]4C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H]([C@H](O)C)C(O)=O)=O)CCCNC(N)=N)=O)CO)=O)CC5=CC=C(C=C5)O)=O)CCC(N)=O)=O)CO)=O)CO)=O)CC(C)C)=O)CC6=CNC=N6)=O)CC7=CNC8=CC=CC=C78)=O)=O)C)=O)CC)=O.O=C([O-])C(F)(F)F
Molecular Formula
C97H131F3I2N20O25S2
Molecular Weight
2352.13
References & Citations
[1]Zahid M, et al., Cardiomyocyte Targeting Peptide to Deliver Amiodarone. bioRxiv [Preprint]. 2023 May 10:2023.05.10.540206. doi: 10.1101/2023.05.10.540206. Update in: Pharmaceutics. 2023 Aug 09;15 (8) :2107.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported

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