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OTOAN rabbit pAb

CAT: 0855-ES14358-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES14358-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is specifically expressed in the inner ear, and is located at the interface between the apical surface of the inner ear sensory epithelia and their overlying acellular gels. It is prposed that this protein is involved in the attachment of the inner ear acellular gels to the apical surface of the underlying nonsensory cells. Mutations in this gene are associated with autosomal recessive deafness type 22 (DFNB22) . Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
Description
The protein encoded by this gene is specifically expressed in the inner ear, and is located at the interface between the apical surface of the inner ear sensory epithelia and their overlying acellular gels. It is prposed that this protein is involved in the attachment of the inner ear acellular gels to the apical surface of the underlying nonsensory cells. Mutations in this gene are associated with autosomal recessive deafness type 22 (DFNB22). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009],
UniProt
Q7RTW8
Swiss Prot
Q7RTW8
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from human OTOAN AA range: 1044-1094
Target
OTOAN
Clonality
Polyclonal
Source
Rabbit
Applications
WB
Concentration
1 mg/ml
Dilution
WB 1:500-2000
Buffer
-20°C/1 year
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Apical cell membrane ; Lipid-anchor, GPI-anchor ; Extracellular side . Secreted, extracellular space, extracellular matrix . At the interface between the apical surface of the epithelia and the overlying acellular gel of the tectorial and otoconial membranes. .
Gene ID (Human)
146183

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