Anticancer agent 204

CAT: 0804-HY-162453Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-162453Size:1 Each
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Description
Anticancer agent 204 (Compound 6), a cinnamide fluorinated derivative, possesses anticancer activity. Anticancer agent 204 can arrest the cell cycle of HepG2 cells in the G1 phase and induce apoptosis by reducing the level of mitochondrial membrane polarization (MMP) [1].
CAS Number
[9007-83-4]
UNSPSC
12352005
Target
Apoptosis; MMP
Type
Reference compound
Related Pathways
Apoptosis; Metabolic Enzyme/Protease
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/anticancer-agent-204.html
Solubility
10 mM in DMSO
Smiles
O=S(C1=CC=C(C=C1)N(C/2=O)C(C3=CC=CC=C3)=NC2=C/C4=CC=C(C=C4)F)(NC5=NC=CC=N5)=O
Molecular Formula
C26H18FN5O3S
Molecular Weight
499.52
References & Citations
[1]Nasser Binjawhar D, et al. Design, Synthesis, and Biological Evaluation of Newly Synthesized Cinnamide-Fluorinated Containing Compounds as Bioactive Anticancer Agents. ACS Omega. 2024;9 (16) :18505-18515. Published 2024 Apr 10.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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