Anticancer agent 204

• Description:

  Anticancer agent 204 (Compound 6), a cinnamide fluorinated derivative, possesses anticancer activity. Anticancer agent 204 can arrest the cell cycle of HepG2 cells in the G1 phase and induce apoptosis by reducing the level of mitochondrial membrane polarization (MMP) [1].

• UNSPSC:

  12352005

• Target:

  Apoptosis; MMP

• Type:

  Reference compound

• Related Pathways:

  Apoptosis; Metabolic Enzyme/Protease

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/anticancer-agent-204.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=S(C1=CC=C(C=C1)N(C/2=O)C(C3=CC=CC=C3)=NC2=C/C4=CC=C(C=C4)F)(NC5=NC=CC=N5)=O

• Molecular Formula:

  C26H18FN5O3S

• Molecular Weight:

  499.52

• References & Citations:

  [1]Nasser Binjawhar D, et al. Design, Synthesis, and Biological Evaluation of Newly Synthesized Cinnamide-Fluorinated Containing Compounds as Bioactive Anticancer Agents. ACS Omega. 2024;9 (16) :18505-18515. Published 2024 Apr 10.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [9007-83-4]