(±) -BAK2-66

• Description:

  (±) -BAK2-66 is a selectivity dopamine D3 receptor antagonist with theKi values of 1nM and 960 nM for D3R and D2R, respectively. (±) -BAK2-66 can be used for study in animal models of addiction[1].

• UNSPSC:

  12352005

• Target:

  Dopamine Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein; Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/racemic-bak2-66.html

• Smiles:

  O=C (NCCC (CN1CCN (CC1) C2=CC=CC (Cl) =C2Cl) F) C3=CC4=CC=CC=C4O3

• Molecular Formula:

  C23H24Cl2FN3O2

• Molecular Weight:

  464.36

• References & Citations:

  [1]Kumar V, et al. Chiral Resolution and Serendipitous Fluorination Reaction for the Selective Dopamine D3 Receptor Antagonist BAK2-66. ACS Med Chem Lett. 2014;5 (6) :647-651. Published 2014 Mar 24.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  1301178-83-5