(±) -BAK2-66

• Description :

  (±) -BAK2-66 is a selectivity dopamine D3 receptor antagonist with theKi values of 1nM and 960 nM for D3R and D2R, respectively. (±) -BAK2-66 can be used for study in animal models of addiction[1].

• UNSPSC :

  12352005

• Target :

  Dopamine Receptor

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein; Neuronal Signaling

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/racemic-bak2-66.html

• Smiles :

  O=C(NCCC(CN1CCN(CC1)C2=CC=CC(Cl)=C2Cl)F)C3=CC4=CC=CC=C4O3

• Molecular Formula :

  C23H24Cl2FN3O2

• Molecular Weight :

  464.36

• References & Citations :

  [1]Kumar V, et al. Chiral Resolution and Serendipitous Fluorination Reaction for the Selective Dopamine D3 Receptor Antagonist BAK2-66. ACS Med Chem Lett. 2014;5 (6) :647-651. Published 2014 Mar 24.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [1301178-83-5]