TFEB activator 1
CAT:
804-HY-135825-02
Size:
100 mg
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
TFEB activator 1
- CAS Number: 39777-61-2
- UNSPSC Description: TFEB activator 1 is an orally effective, mTOR-independent activator of TFEB. TFEB activator 1 significantly promotes the nuclear translocation of Flag-TFEB with an EC50 of 2167 nM. TFEB activator 1 enhances autophagy without inhibiting the mTOR pathway and has the potential for neurodegenerative diseases treatment[1].
- Target Antigen: Autophagy
- Type: Reference compound
- Related Pathways: Autophagy
- Field of Research: Neurological Disease
- Assay Protocol: https://www.medchemexpress.com/tfeb-activator-1.html
- Smiles: O=C(/C=C/C1=CC=CC=C1OC)/C=C/C2=CC=CC=C2OC
- Molecular Weight: 294.34
- References & Citations: [1]Song JX, et al. A novel curcumin analog binds to and activates TFEB in vitro and in vivo independent of MTOR inhibition. Autophagy. 2016 Aug 2;12(8):1372-89.
- Shipping Conditions: Room Temperature