Sulfo-SPP

• Description :

  Sulfo-SPP is a heterobifunctional, thiol-cleavable and membrane impermeable crosslinker.

• CAS Number :

  [452072-27-4]

• UNSPSC :

  12352203

• Hazard Statement :

  H302-H315-H319-H335

• Target :

  ADC Linker

• Type :

  ADC Related

• Related Pathways :

  Antibody-drug Conjugate/ADC Related

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/sulfo-spp.html

• Purity :

  97.14

• Solubility :

  10 mM in DMSO

• Smiles :

  CC(SSC1=NC=CC=C1)CCC(ON2C(C(S(=O)(O)=O)CC2=O)=O)=O

• Molecular Formula :

  C14H16N2O7S3

• Molecular Weight :

  420.48

• Precautions :

  P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

• References & Citations :

  [1]Ravi V. J. Chari, et al. Methods for preparation of cytotoxic conjugates of maytansinoids and cell binding agents. US6441163B1.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, sealed storage, away from moisture and light)

• Scientific Category :

  ADC Related

• Clinical Information :

  No Development Reported

• Isoform :

  Cleavable Linker; Disulfide Cleavable Linker