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Actinine-d9 (chloride)

CAT: 0804-HY-113270AS-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-113270AS-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Actinine-d9 chloride is the deuterium labeled Actinine chloride. Actinine chloride is angiopathic substance produced as an intermediary metabolite by gut microbiota that feed on carnitine in dietary red meat[1][2].
CAS Number
85806-17-3
Product Name Alternative
γ-Butyrobetaine-d9 (hydrochloride) ; Deoxycarnitine-d9 (hydrochloride)
UNSPSC
12352211
Target
Endogenous Metabolite
Type
Isotope-Labeled Compounds
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Metabolic Disease; Cardiovascular Disease
Purity
98.01
Solubility
DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
[2H]C([N+](C([2H])([2H])[2H])(C([2H])([2H])[2H])CCCC(O)=O)([2H])[2H].[Cl-]
Molecular Formula
C7H7D9ClNO2
Molecular Weight
190.72
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Koeth RA, et al. γ-Butyrobetaine is a proatherogenic intermediate in gut microbial metabolism of L-carnitine to TMAO. Cell Metab. 2014 Nov 4;20 (5) :799-812.|[3]Susumu Ogawa, et al. The Dynamics of Carnitine, γ-butyrobetaine and Trimethylamine N-oxide in Diabetics and the Effects of Changes in Renal Function. Ogawa et al., J Nephrol Ren Dis 2017, 1:2
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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