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Actinine (chloride)

CAT: 0804-HY-113270A-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-113270A-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Actinine (γ-Butyrobetaine) chloride is angiopathic substance produced as an intermediary metabolite by gut microbiota that feed on carnitine in dietary red meat.

Actinine chloride, also known as γ-Butyrobetaine chloride or Deoxycarnitine chloride, is an endogenous and microbial metabolite involved in L-carnitine metabolism. γ-Butyrobetaine is an important intermediate in the gut microbial pathway that converts L-carnitine into trimethylamine (TMA) and subsequently trimethylamine N-oxide (TMAO).
CAS Number
6249-56-5
Product Name Alternative
γ-Butyrobetaine (chloride) ; Deoxycarnitine (chloride)
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
Endogenous Metabolite
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Metabolic Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/actinine-chloride.html
Purity
98.0
Solubility
DMSO : 30 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)
Smiles
C[N+](C)(C)CCCC(O)=O.[Cl-]
Molecular Formula
C7H16ClNO2
Molecular Weight
181.66
Precautions
H302, H315, H319, H335
References & Citations
[1]Koeth RA, et al. γ-Butyrobetaine is a proatherogenic intermediate in gut microbial metabolism of L-carnitine to TMAO. Cell Metab. 2014 Nov 4;20 (5) :799-812.|[2]Susumu Ogawa, et al. The Dynamics of Carnitine, γ-butyrobetaine and Trimethylamine N-oxide in Diabetics and the Effects of Changes in Renal Function. Ogawa et al., J Nephrol Ren Dis 2017, 1:2
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Natural Products
Clinical Information
No Development Reported
FAQ
What is Actinine chloride? => Actinine chloride is the chloride salt of γ-butyrobetaine, a metabolite associated with both endogenous carnitine biosynthesis and microbial L-carnitine metabolism. What is γ-Butyrobetaine? => γ-Butyrobetaine is an intermediate in the microbial metabolism of L-carnitine to TMA, which can subsequently be converted by the host to TMAO. What is the CAS number of Actinine chloride? => The CAS number is 6249-56-5. What are the main research areas for Actinine chloride? => It is mainly relevant to gut microbiota, metabolomics, carnitine metabolism, TMA/TMAO research and cardiovascular metabolism.

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