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(±) -Carnitine-d9 (chloride)

CAT: 0804-HY-B1453S1-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B1453S1-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
(±) -Carnitine-d9 (chloride) is the deuterium labeled (±) -Carnitine chloride. (±) -Carnitine chloride exists in two isomers, known as D and L. L-carnitine plays an essential role in the β-oxidation of fatty acids and also shows antioxidant, and anti-inflammatory activities.
CAS Number
1219386-75-0
Product Name Alternative
DL-Carnitine-d9 (chloride)
UNSPSC
12352211
Hazard Statement
H315, H319, H335
Target
Reactive Oxygen Species (ROS)
Type
Isotope-Labeled Compounds
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Field of Research
Metabolic Disease
Purity
99.0
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
[2H]C([2H])([2H])[N+](C([2H])([2H])[2H])(C([2H])([2H])[2H])CC(O)CC(O)=O.[Cl-]
Molecular Formula
C7H7D9ClNO3
Molecular Weight
206.72
Precautions
H315, H319, H335
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Oyanagi E, et al. Protective action of L-carnitine on cardiac mitochondrial function and structure against fatty acidstress. Biochem Biophys Res Commun. 2011 Aug 19;412 (1) :61-7.|[3]Li J, et al. l-carnitine protects human hepatocytes from oxidative stress-induced toxicity through Akt-mediated activation of Nrf2 signaling pathway. Can J Physiol Pharmacol. 2016 May;94 (5) :517-25.|[4]Jang J, et al. l-Carnitine supplement reduces skeletal muscle atrophy induced by prolonged hindlimb suspension in rats. Appl Physiol Nutr Metab. 2016 Dec;41 (12) :1240-1247.|[5]Zambrano S, et al. L-carnitine attenuates the development of kidney fibrosis in hypertensive rats by upregulating PPAR-γ. Am J Hypertens. 2014 Mar;27 (3) :460-70.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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