(E/Z) -MCB-613

CAT: 0804-HY-19625A-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-19625A-01Size:1 mg
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AVAILABILITY: InStock
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Description
(E/Z) -MCB-613 is a pan-Steroid Receptor Coactivator (SRC) stimulator. (E/Z) -MCB-613 overstimulates SRC activity in cancer cells resulting in excessive generation of reactive oxygen species (ROS), leading to cell stress and death by a process called paraptosis. (E/Z) -MCB-613 is a cytotoxic molecule that plays an important role in cancer[1].
CAS Number
[296792-62-6]
UNSPSC
12352005
Target
Paraptosis; Reactive Oxygen Species (ROS)
Type
Reference compound
Related Pathways
Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/e-z-mcb-613.html
Solubility
10 mM in DMSO
Smiles
O=C1/C(CC(CC)C/C1=C\C2=CC=CN=C2)=C/C3=CC=CN=C3
Molecular Formula
C20H20N2O
Molecular Weight
304.39
References & Citations
[1]Lei Wang, et al. Characterization of a Steroid Receptor Coactivator Small Molecule Stimulator that Overstimulates Cancer Cells and Leads to Cell Stress and Death. Cancer Cell. 2015 Aug 10;28 (2) :240-52.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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