MCB-613

CAT: 0804-HY-19625-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-19625-01Size:5 mg
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Description
MCB-613 is a potent Steroid receptor coactivator SRC small molecule ‘stimulator’ (SMS), super-stimulates SRCs’ transcriptional activity. MCB-613 increases SRCs’ interactions with other coactivators and markedly induces ER stress coupled to the generation of reactive oxygen species (ROS) . MCB-613 is a SMS that target oncogenes can be exploited as anti-cancer agents by over-stimulating the SRC oncogenic program[1].
CAS Number
[1162656-22-5]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Paraptosis; Reactive Oxygen Species (ROS)
Type
Reference compound
Related Pathways
Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/MCB-613.html
Purity
99.64
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C1/C(CC(CC)C/C1=C\C2=CC=CN=C2)=C/C3=CC=CN=C3
Molecular Formula
C20H20N2O
Molecular Weight
304.39
Precautions
H302, H315, H319, H335
References & Citations
[1]Wang L, et al. Characterization of a Steroid Receptor Coactivator Small Molecule Stimulator that Overstimulates Cancer Cells and Leads to Cell Stress and Death. Cancer Cell. 2015 Aug 10;28 (2) :240-52.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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