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NED-3238

CAT: 0804-HY-126332Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-126332Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
NED-3238 is a highly potent arginase I and II inhibitor with IC50 values of 1.3 nM and 8.1 nM, respectively[1].
CAS Number
[2389062-09-1]
UNSPSC
12352005
Target
Arginase
Type
Reference compound
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/ned-3238.html
Solubility
10 mM in DMSO
Smiles
O=C([C@]1(N)CN(C[C@@H](N)CC2=CC=CC=C2)C[C@@H]1CCCB(O)O)O
Molecular Formula
C17H28BN3O4
Molecular Weight
349.23
References & Citations
[1]Van Zandt MC, et al. Discovery of N-Substituted 3-Amino-4- (3-boronopropyl) pyrrolidine-3-carboxylic Acids as Highly Potent Third-Generation Inhibitors of Human Arginase I and II. J Med Chem. 2019 Aug 23.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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