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CCR-11

CAT: 0804-HY-119648Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-119648Size:1 Each
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Description
CCR-11 is an antibacterial agent. CCR-11 can inhibit the proliferation of B. subtilis cells with an IC50 value of 1.2 μM. CCR-11 inhibits HeLa cell proliferation with an IC50 value of 18.1 μM. CCR-11 inhibits bacterial cytokinesis by inhibiting FtsZ assembly. CCR-11 can be used for the research of FtsZ-targeted antibacterial agents[1].
CAS Number
1287652-03-2
Product Name Alternative
BE-34776
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/ccr-11.html
Solubility
10 mM in DMSO
Smiles
O=C1NC(S/C1=C/C2=CC=C(C3=CC=CC(C(F)(F)F)=C3)O2)=S
Molecular Formula
C15H8F3NO2S2
Molecular Weight
355.35
References & Citations
[1]Singh P, et al. A rhodanine derivative CCR-11 inhibits bacterial proliferation by inhibiting the assembly and GTPase activity of FtsZ. Biochemistry. 2012 Jul 10;51 (27) :5434-42.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported