CCR-11

• Description:

  CCR-11 is an antibacterial agent. CCR-11 can inhibit the proliferation of B. subtilis cells with an IC50 value of 1.2 μM. CCR-11 inhibits HeLa cell proliferation with an IC50 value of 18.1 μM. CCR-11 inhibits bacterial cytokinesis by inhibiting FtsZ assembly. CCR-11 can be used for the research of FtsZ-targeted antibacterial agents[1].

• Product Name Alternative:

  BE-34776

• UNSPSC:

  12352005

• Target:

  Bacterial

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/ccr-11.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C1NC(S/C1=C/C2=CC=C(C3=CC=CC(C(F)(F)F)=C3)O2)=S

• Molecular Formula:

  C15H8F3NO2S2

• Molecular Weight:

  355.35

• References & Citations:

  [1]Singh P, et al. A rhodanine derivative CCR-11 inhibits bacterial proliferation by inhibiting the assembly and GTPase activity of FtsZ. Biochemistry. 2012 Jul 10;51 (27) :5434-42.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [1287652-03-2]