PSB-SB-487

• Description :

  PSB-SB-487 is a potent GPR55 antagonist and CB2 agonist with an IC50 value of 0.113 µM for GPR55, and a Ki value of 0.292 µM for human CB2. PSB-SB-487 can be used for researching diabetes, Parkinson’s disease, neuropathic pain, and cancer[1].

• UNSPSC :

  12352005

• Target :

  Cannabinoid Receptor; GPR55

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein; Neuronal Signaling

• Applications :

  Metabolism-protein/nucleotide metabolism

• Field of Research :

  Cancer; Metabolic Disease; Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/psb-sb-487.html

• Purity :

  98.01

• Solubility :

  DMSO : 100 mg/mL (ultrasonic)

• Smiles :

  O=C1C(CC2=CC=CC=C2O)=CC3=C(O)C=C(C(C)(C)CCCCCCC)C=C3O1

• Molecular Formula :

  C26H32O4

• Molecular Weight :

  408.53

• References & Citations :

  [1]Viktor Rempel, et al. Antagonists for the orphan G-protein-coupled receptor GPR55 based on a coumarin scaffold. J Med Chem. 2013 Jun 13;56 (11) :4798-810.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [1399049-81-0]