HI-TOPK-032

• UNSPSC Description:

  HI-TOPK-032 is a potent and specific TOPK inhibitor.

• Target Antigen:

  TOPK

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/HI-TOPK-032.html

• Purity:

  98.83

• Solubility:

  DMSO : 2.5 mg/mL (ultrasonic;warming;heat to 60°C)

• Smiles:

  O=C(C1=CC=CS1)NC2=CC3=C(C#N)C4=NC5=CC=CC=C5N=C4N3C=C2

• Molecular Weight:

  369.40

• References & Citations:

  [1]Kim DJ, et al. Novel TOPK inhibitor HI-TOPK-032 effectively suppresses colon cancer growth. Cancer Res. 2012 Jun 15;72(12):3060-8.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  487020-03-1