XW-032

• Description :

  XW-032 is an apo-IDO1 inhibitor, with an IC50 of 21 nM. XW-032 (TGI = 63%) exhibits potent in vivo anti-tumor efficacy in the CT26 syngeneic mouse model and is expected to be applied in the research of the field of cancer[1].

• UNSPSC :

  12352005

• Target :

  Indoleamine 2,3-Dioxygenase (IDO)

• Related Pathways :

  Metabolic Enzyme/Protease

• Field of Research :

  Cancer

• Smiles :

  O=C(CCCC1=CC=C(C=C1)C2=NC=C(C=C2)F)NC3=CC=C(C=C3)F

• Molecular Formula :

  C21H18F2N2O

• Molecular Weight :

  352.38

• References & Citations :

  [1]Cen L, et al. Discovery and Optimization of Novel Apo-IDO1 Inhibitors by a Pharmacophore-Based Structural Simplification Strategy. J Med Chem. 2025 Mar 5.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported