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HSD17B13-IN-75

CAT: 0804-HY-161230Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-161230Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
HSD17B13-IN-75 (Compound 21) is an inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) with an IC50 value of ≤ 0.1 μM for estradiol. HSD17B13-IN-75 can be used for research on liver diseases, metabolic diseases, or cardiovascular diseases, such as NAFLD or NASH, as well as drug-induced liver injury (DILI) [1].
CAS Number
2770246-20-1
UNSPSC
12352005
Target
17β-HSD
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/hsd17b13-in-75.html
Solubility
10 mM in DMSO
Smiles
OC1=C(Cl)C=C(C(NC2=CC=CC3=C2C(N(C4(CC4)C5=CC=CC=C5F)C=N3)=O)=O)C=C1Cl
Molecular Formula
C24H16Cl2FN3O3
Molecular Weight
484.31
References & Citations
[1]Anandan S K, et al. Dichlorophenol HSD17B13 inhibitors and uses thereof. U.S., WO2022103960. 2023-11-28.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported