HSD17B13-IN-12

HSD17B13-IN-12

• CAS Number: 2758802-04-7
• UNSPSC Description: HSD17B13-IN-12 (Compound 3) is an inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) with an IC50 value of ≤ 0.1 μM for both leukotriene B3 and estradiol. HSD17B13-IN-12 can be used in the research of liver diseases, metabolic disorders, or cardiovascular diseases such as NAFLD or NASH, or drug-induced liver injury (DILI)[1].
• Target Antigen: 17β-HSD
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Metabolism-protein/nucleotide metabolism
• Field of Research: Metabolic Disease
• Assay Protocol: https://www.medchemexpress.com/hsd17b13-in-12.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(NCCC(C)(C)C)C1=C(NC(C2=CC(Cl)=C(O)C=C2)=O)C=CS1
• Molecular Weight: 380.89
• References & Citations: [1]Odingo J, et al. Thiophene hsd17b13 inhibitors and uses thereof. U.S., WO2022020714. 2023-09-07.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported