MK-761 (free base)

MK-761 (free base)

• CAS Number: 65321-41-7
• UNSPSC Description: MK-761 free base is a potent and orally active β2-adrenergic blocker. MK-761 free base shows antihypertensive and positive inotropic effects. MK-761 free base shows vasodilating properties[1].
• Target Antigen: Adrenergic Receptor
• Type: Reference compound
• Related Pathways: GPCR/G Protein;Neuronal Signaling
• Field of Research: Cardiovascular Disease
• Assay Protocol: https://www.medchemexpress.com/mk-761-free-base.html
• Purity: 99.56
• Solubility: DMSO : 100 mg/mL (ultrasonic)
• Smiles: N#CC1=CC=CN=C1OC[C@H](CNC(C)(C)C)O
• Molecular Weight: 249.31
• References & Citations: [1]Scriabine A, et al. Antihypertensive and cardiac effects of two novel beta-adrenoceptor blocking drugs. Experientia. 1979 Dec 15;35(12):1634-7. |[2]C.S. Sweet, et al. Peripheral Vasodilator and β-Adrenoceptor Blocking Properties of Several β-Adrenoceptor Antagonists. Clinical and Experimental Hypertension. 2009, 449-471.|[3]Sweet CS, et al. Beta adrenoceptor blocking properties of MK-761. J Pharmacol Exp Ther. 1979 Oct;211(1):195-9.
• Shipping Conditions: Blue Ice
• Storage Conditions: -20°C, 3 years (Powder)
• Clinical Information: No Development Reported