YTHDC2 Human Recombinant

YTHDC2 Human Recombinant_x000D_ Catalog number: B2017403_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Amount: 100 µg_x000D_ Molecular Weight or Concentration: 42.13 kDa_x000D_ Supplied as: Solution_x000D_ Applications: a molecular tool for various biochemical applications_x000D_ Storage: -80°C_x000D_ Keywords: CsA-Associated Helicase-Like Protein, hYTHDC2, Probable ATP-Dependent RNA Helicase YTHDC2, 3'-5' RNA Helicase YTHDC2, YTH Domain-Containing Protein 2_x000D_ Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: Sun S, Han Q, Liang M, Zhang Q, Zhang J, Cao J. Downregulation of m(6) A reader YTHDC2 promotes tumor progression and predicts poor prognosis in non-small cell lung cancer Thorac Cancer. 2020 Nov;11(11):3269-3279._x000D_ 2: Zhu J, Liu S, Fang J, Cui Z, Wang B, Wang Y, Liu L, Wang Q, Cao X. Enzymolysis-based RNA pull-down identifies YTHDC2 as an inhibitor of antiviral innate response Cell Rep. 2023 Oct 31;42(10):113192._x000D_ 3: Ming X, Chen S, Li H, Wang Y, Zhou L, Lv Y. m6A RNA Methylation and Implications for Hepatic Lipid Metabolism DNA Cell Biol. 2024 Jun;43(6):271-278._x000D_ 4: Morohashi K, Sahara H, Watashi K, Iwabata K, Sunoki T, Kuramochi K, Takakusagi K, Miyashita H, Sato N, Tanabe A, Shimotohno K, Kobayashi S, Sakaguchi K, Sugawara F. Cyclosporin A associated helicase-like protein facilitates the association of hepatitis C virus RNA polymerase with its cellular cyclophilin B PLoS One. 2011 Apr 29;6(4):e18285._x000D_ 5: Tanabe A, Nakayama T, Kashiyanagi J, Yamaga H, Hirohashi Y, Torigoe T, Satomi F, Shima H, Maeda H, Kutomi G, Takemasa I, Sahara H. YTHDC2 Promotes Malignant Phenotypes of Breast Cancer Cells J Oncol. 2022 Oct 7;2022:9188920._x000D_ 6: Ma L, Chen T, Zhang X, Miao Y, Tian X, Yu K, Xu X, Niu Y, Guo S, Zhang C, Qiu S, Qiao Y, Fang W, Du L, Yu Y, Wang J. The m(6)A reader YTHDC2 inhibits lung adenocarcinoma tumorigenesis by suppressing SLC7A11-dependent antioxidant function Redox Biol. 2021 Jan;38:101801._x000D_ 7: Hsu PJ, Zhu Y, Ma H, Guo Y, Shi X, Liu Y, Qi M, Lu Z, Shi H, Wang J, Cheng Y, Luo G, Dai Q, Liu M, Guo X, Sha J, Shen B, He C. Ythdc2 is an N(6)-methyladenosine binding protein that regulates mammalian spermatogenesis Cell Res. 2017 Sep;27(9):1115-1127._x000D_ 8: Li L, Krasnykov K, Homolka D, Gos P, Mendel M, Fish RJ, Pandey RR, Pillai RS. The XRN1-regulated RNA helicase activity of YTHDC2 ensures mouse fertility independently of m(6)A recognition Mol Cell. 2022 May 5;82(9):1678-1690.e12._x000D_ 9: Saito Y, Hawley BR, Puno MR, Sarathy SN, Lima CD, Jaffrey SR, Darnell RB, Keeney S, Jain D. YTHDC2 control of gametogenesis requires helicase activity but not m(6)A binding Genes Dev. 2022 Feb 1;36(3-4):180-194._x000D_ 10: Wang J, Tan L, Yu X, Cao X, Jia B, Chen R, Li J. lncRNA ZNRD1-AS1 promotes malignant lung cell proliferation, migration, and angiogenesis via the miR-942/TNS1 axis and is positively regulated by the m(6)A reader YTHDC2 Mol Cancer. 2022 Dec 30;21(1):229. _x000D_ _x000D_ Products Related to YTHDC2 Human Recombinant can be found at Proteins

9000-83-3

Catalog Number: B2017403 (100 µg)

0.15

2

0.5