EIF4E Human Recombinant

• Description:

  eIF4E Human Recombinant_x000D_ Catalog number: B2017244_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Amount: 100 µg_x000D_ Molecular Weight or Concentration: 27.19 kDa_x000D_ Supplied as: Solution_x000D_ Applications: a molecular tool for various biochemical applications_x000D_ Storage: -80°C_x000D_ Keywords: Eukaryotic Translation Initiation Factor 4E, mRNA Cap-binding Protein_x000D_ Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: Julius A, Desai A, Yung RL. Recombinant human erythropoietin stimulates melanoma tumor growth through activation of initiation factor eIF4E Oncotarget. 2017 May 2;8(18):30317-30327._x000D_ 2: Eckerdt F, Beauchamp E, Bell J, Iqbal A, Su B, Fukunaga R, Lulla RR, Goldman S, Platanias LC. Regulatory effects of a Mnk2-eIF4E feedback loop during mTORC1 targeting of human medulloblastoma cells Oncotarget. 2014 Sep 30;5(18):8442-51._x000D_ 3: Wan J, Shi F, Xu Z, Zhao M. Knockdown of eIF4E suppresses cell proliferation, invasion and enhances cisplatin cytotoxicity in human ovarian cancer cells Int J Oncol. 2015 Dec;47(6):2217-25._x000D_ 4: Hughes JM, Ptushkina M, Karim MM, Koloteva N, von der Haar T, McCarthy JE. Translational repression by human 4E-BP1 in yeast specifically requires human eIF4E as target J Biol Chem. 1999 Feb 5;274(6):3261-4._x000D_ 5: Tan J, Ye J, Song M, Zhou M, Hu Y. Ribavirin augments doxorubicin's efficacy in human hepatocellular carcinoma through inhibiting doxorubicin-induced eIF4E activation J Biochem Mol Toxicol. 2018 Jan;32(1)._x000D_ 6: Dong K, Wang R, Wang X, Lin F, Shen JJ, Gao P, Zhang HZ. Tumor-specific RNAi targeting eIF4E suppresses tumor growth, induces apoptosis and enhances cisplatin cytotoxicity in human breast carcinoma cells Breast Cancer Res Treat. 2009 Feb;113(3):443-56._x000D_ 7: Wongsombat C, Yingchutrakul Y, Suwanakitti N, Leetanasaksakul K, Roytrakul S, Shaw PJ, Aroonsri A. Identification of mRNA 5' cap-associated proteins in the human malaria parasite Plasmodium falciparum Mol Biochem Parasitol. 2022 Jan;247:111443._x000D_ 8: Shaw PJ, Ponmee N, Karoonuthaisiri N, Kamchonwongpaisan S, Yuthavong Y. Characterization of human malaria parasite Plasmodium falciparum eIF4E homologue and mRNA 5' cap status Mol Biochem Parasitol. 2007 Oct;155(2):146-55._x000D_ 9: Pyronnet S, Imataka H, Gingras AC, Fukunaga R, Hunter T, Sonenberg N. Human eukaryotic translation initiation factor 4G (eIF4G) recruits mnk1 to phosphorylate eIF4E EMBO J. 1999 Jan 4;18(1):270-9._x000D_ 10: Youtani T, Tomoo K, Ishida T, Miyoshi H, Miura K. Regulation of human eIF4E by 4E-BP1: binding analysis using surface plasmon resonance IUBMB Life. 2000 Jan;49(1):27-31. _x000D_ _x000D_ Products Related to eIF4E Human Recombinant can be found at Proteins

• Short Description:

  Catalog Number: B2017244 (100 µg)

• Weight:

  0.15

• Length:

  2

• Width:

  0.5

• Height:

  0.5

• Height :

  0.5

• CAS Number:

  9000-83-3