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TIM50 rabbit pAb

CAT: 0855-ES12695-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES12695-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a subunit of the TIM23 inner mitochondrial membrane translocase complex. The encoded protein functions as the receptor subunit that recognizes the mitochondrial targeting signal, or presequence, on protein cargo that is destined for the mitochondrial inner membrane and matrix. This protein may also play a role in maintaining the membrane permeability barrier, and knockdown of this gene in human cells results in the release of cytochrome c and apoptosis. [provided by RefSeq, Jul 2016]
Description
This gene encodes a subunit of the TIM23 inner mitochondrial membrane translocase complex. The encoded protein functions as the receptor subunit that recognizes the mitochondrial targeting signal, or presequence, on protein cargo that is destined for the mitochondrial inner membrane and matrix. This protein may also play a role in maintaining the membrane permeability barrier, and knockdown of this gene in human cells results in the release of Cytochrome c and apoptosis. [provided by RefSeq, Jul 2016],
Product Name Alternative
Mitochondrial import inner membrane translocase subunit TIM50
UniProt
Q3ZCQ8
Swiss Prot
Q3ZCQ8
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from human TIM50 AA range: 109-159
Target
TIM50
Clonality
Polyclonal
Source
Rabbit
Applications
WB
Concentration
1 mg/ml
Dilution
WB 1:500-2000
Buffer
-20°C/1 year
Molecular Weight
38kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
38kD
Fragment
IgG
Subcellular Location
Mitochondrion inner membrane ; Single-pass membrane protein .; [Isoform 2]: Nucleus speckle . Nuclear and enriched in speckles with snRNPs. .
Other Product Names
Mitochondrial import inner membrane translocase subunit TIM50
Gene ID (Human)
92609

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