TIM50 rabbit pAb

• Background:

  This gene encodes a subunit of the TIM23 inner mitochondrial membrane translocase complex. The encoded protein functions as the receptor subunit that recognizes the mitochondrial targeting signal, or presequence, on protein cargo that is destined for the mitochondrial inner membrane and matrix. This protein may also play a role in maintaining the membrane permeability barrier, and knockdown of this gene in human cells results in the release of cytochrome c and apoptosis. [provided by RefSeq, Jul 2016]

• Description:

  This gene encodes a subunit of the TIM23 inner mitochondrial membrane translocase complex. The encoded protein functions as the receptor subunit that recognizes the mitochondrial targeting signal, or presequence, on protein cargo that is destined for the mitochondrial inner membrane and matrix. This protein may also play a role in maintaining the membrane permeability barrier, and knockdown of this gene in human cells results in the release of Cytochrome c and apoptosis. [provided by RefSeq, Jul 2016],

• UniProt:

  Q3ZCQ8

• Swiss Prot:

  Q3ZCQ8

• Reactivity:

  Human; Mouse

• Immunogen:

  Synthesized peptide derived from human TIM50 AA range: 109-159

• Clonality:

  Polyclonal

• Source:

  Rabbit

• Applications:

  WB

• Concentration:

  1 mg/ml

• Dilution:

  WB 1:500-2000

• Molecular Weight:

  38kD

• Storage Conditions:

  -20°C/1 year

• Observed Molecular Weight:

  38kD

• Fragment:

  IgG

• Subcellular Location:

  Mitochondrion inner membrane ; Single-pass membrane protein .; [Isoform 2]: Nucleus speckle . Nuclear and enriched in speckles with snRNPs. .

• Other Product Names:

  Mitochondrial import inner membrane translocase subunit TIM50

• Gene ID (Human):

  92609