[Tyr8,Nle11] Substance P

• UNSPSC Description:

  [Tyr8,Nle11] Substance P is a Substance P (HY-P0201) analog. Substance P is a peptide mainly secreted by neurons and is involved in many biological processes, including nociception and inflammation[1].

• Target Antigen:

  Neurokinin Receptor

• Type:

  Peptides

• Related Pathways:

  GPCR/G Protein;Neuronal Signaling

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology; Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/tyr8-nle11-substance-p.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C([C@H]1N(CCC1)C([C@@H](N)CCCNC(N)=N)=O)N[C@@H](CCCCN)C(N2[C@@H](CCC2)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCC(N)=O)C(N[C@H](C(N[C@H](C(NCC(N[C@@H](CC(C)C)C(N[C@H](C(N)=O)CCCC)=O)=O)=O)CC3=CC=C(C=C3)O)=O)CC4=CC=CC=C4)=O)=O)=O)=O

• Molecular Weight:

  1345.59

• References & Citations:

  [1]Mashaghi A, et al. Neuropeptide substance P and the immune response. Cell Mol Life Sci. 2016 Nov;73(22):4249-4264.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  71890-48-7