CXCR2 antagonist 2

CXCR2 antagonist 2

• CAS Number: 2647464-91-1
• UNSPSC Description: CXCR2 antagonist 2 is a potent CXCR2 antagonist for cancer immunoresearch with an IC50 value of 95 nM.
• Target Antigen: CXCR
• Type: Reference compound
• Related Pathways: GPCR/G Protein;Immunology/Inflammation
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/cxcr2-antagonist-2.html
• Solubility: DMSO : 100 mg/mL (ultrasonic)
• Smiles: O=S1(C2=C(O)C(NC(NC3=CC=CC(F)=C3C)=O)=CC=C2CCC1)=O
• Molecular Weight: 364.39
• References & Citations: [1]Dong Y, et al. Discovery of Benzocyclic Sulfone Derivatives as Potent CXCR2 Antagonists for Cancer Immunotherapy. J Med Chem. 2021 Nov 25;64(22):16626-16640.
• Shipping Conditions: Room Temperature
• Clinical Information: No Development Reported