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CXCR2 antagonist 3

CAT: 0931-T61356-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T61356-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2647464-92-2
Target
CXCR, Others
Related Pathways
GPCR/G Protein, Others, Autophagy, Immunology/Inflammation
Bioactivity
CXCR2 antagonist 3 (compound 11h) is a highly effective inhibitor of CXC chemokine receptor 2 (CXCR2), displaying double-digit nanomolar potencies in inhibiting neutrophil infiltration into the air pouch. Additionally, it reduces neutrophil and MDSC infiltration while enhancing CD3+ T lymphocyte infiltration into Pan02 tumor tissues [1].
Smiles
OC1=C2C(=CC=C1NC(NC3=C(C)C(F)=CC=C3)=O)C=CCS2(=O)=O
Molecular Formula
C17H15FN2O4S
Molecular Weight
362.38
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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