Mirogabalin-d4

• Description :

  Mirogabalin-d4 (DS5565-d4) is a deuterated compound of Mirogabalin (HY-12650), a ligand that selectively targets the voltage-sensitive calcium channel complex α2δ-1[1][2].

• Product Name Alternative :

  DS5565-d4

• UNSPSC :

  12352211

• Target :

  Calcium Channel; Isotope-Labeled Compounds

• Type :

  Isotope-Labeled Compounds

• Related Pathways :

  Membrane Transporter/Ion Channel; Neuronal Signaling; Others

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Smiles :

  CCC1=C[C@H]2[C@](C([2H])([2H])C(O)=O)(C(N)([2H])[2H])C[C@H]2C1

• Molecular Formula :

  C12H15D4NO2

• Molecular Weight :

  213.31

• References & Citations :

  [1]Vinik A, et al. Efficacy and safety of Mirogabalin (DS-5565) for the treatment of diabetic peripheral neuropathic pain: a randomized, double-blind, placebo- and active comparator-controlled, adaptive proof-of-concept phase 2 study. Diabetes Care. 2014 Dec.|[2]Hutmacher MM, et al. Exposure-response modeling of average daily pain score, and dizziness and somnolence, forMirogabalin (DS-5565) in patients with diabetic peripheral neuropathic pain. J Clin Pharmacol. 2016 Jan;56 (1) :67-77.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Isotope-Labeled Compounds

• Clinical Information :

  No Development Reported