Tyrphostin 47

• UNSPSC Description:

  Tyrphostin 47 is a nonspecific inhibitor of WNK1. Tyrphostin 47 is a protein tyrosine kinase inhibitor. Tyrphostin 47 inhibits smooth-muscle cell proliferation[1][2]

• Target Antigen:

  Ser/Thr Protease

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/tyrphostin-47.html

• Smiles:

  S=C(N)/C(C#N)=C/C1=CC=C(O)C(O)=C1

• Molecular Weight:

  220.25

• References & Citations:

  [1]Erfinanda L, et al. Loss of endothelial CFTR drives barrier failure and edema formation in lung infection and can be targeted by CFTR potentiation. Sci Transl Med. 2022 Dec 7;14(674):eabg8577.|[2]Gottsauner-Wolf M, et al. Influence of local delivery of the protein tyrosine kinase receptor inhibitor tyrphostin-47 on smooth-muscle cell proliferation in a rat carotid balloon-injury model. Am Heart J. 1997 Mar;133(3):329-34.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  118409-60-2