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CK-636

CAT: 0804-HY-15892-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-15892-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CK-636 is a cell permeable inhibitor of Arp2/3 complex, that could inhibit actin polymerization, with IC50 values of 4 μM, 24 μM and 32 μM for human, fission yeast and bovine, respectively. CK636 blocks cell migration.
CAS Number
442632-72-6
Product Name Alternative
CK-0944636
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Arp2/3 Complex
Type
Reference compound
Related Pathways
Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/CK-636.html
Purity
99.95
Solubility
DMSO : ≥ 49 mg/mL
Smiles
O=C(C1=CC=CS1)NCCC2=C(C)NC3=C2C=CC=C3
Molecular Formula
C16H16N2OS
Molecular Weight
284.38
Precautions
H302, H315, H319, H335
References & Citations
[1]Nolen BJ, et al. Characterization of two classes of small molecule inhibitors of Arp2/3 complex. Nature. 2009 Aug 20;460 (7258) :1031-4.|[2]Kwon KW, et al. Migration of T cells on surfaces containing complex nanotopography. PLoS One. 2013 Sep 12;8 (9) :e73960.|[3]Liang Ma, et al. Discovery of the migrasome, an organelle mediating release of cytoplasmic contents during cell migration. Cell Res. 2015 Jan;25 (1) :24-38.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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Alternative Products

CatalogName
B3058-10CK-636
MBS130476-01CK-636(CK-0944636
A13827-50CK-636 50mg
A13827-5CK-636 5mg
A13827-500CK-636 500mg
A13827-100CK-636 100mg
A13827-10CK-636 10mg
A13827-25CK-636 25mg

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